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Williams PhDMV, Cox B, Lafuse PhD WP, Ariza ME

Indications: Terrorism / Chemical Warfare, Weapon of Mass Destruction Effects: Remember muscarinic & nicotinic symptoms SLUDE Symptoms will appear within a few seconds after exposure to the vapor form of sarin and within a few minutes to up to 18 hours after exposure to the liquid form (see below) A long term study of soldiers exposed to sarin & cyclosarin during the first Gulf War (1991) indicated that exposure was significantly associated with less proficient neurobehavioral functioning on tasks involving fine psychomotor dexterity and visuospatial abilities 45 years after exposure (Proctor et al, 2007)

To address challenges by their low copy number, we develop AETX-R114, a T cell engaging bispecific antibody with picomolar affinity for MHC-restricted sotorasib-modified KRAS G12C peptides presented by three HLA-A3 supertype alleles

Accountability matters