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To date, there is only one approved medication available to treat ALS, namely riluzole, which only increases survival by 3 months (Bensimon et al., Energy metabolism disturbances in ALS There are many lines of evidence for the role of disturbed energy metabolism in ALS pathogenesis
(PubMed) Kuriti M, Pearce EN, Braverman LE, He X, Leung AM
Quantitative PCR analysis of mitochondrial DNA content in patients with mitochondrial disease
