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997 As noted in the Mortality and Morbidity section, a person who lives from age 70 to age 80 with Alzheimer's dementia will spend an average of 40% of this time in the severe stage
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If these conditions are severe or left untreated, they can cause lifelong nerve damage or even death
The first pass through the liver generally greatly reduces the bioavailability, as only a small amount of active drug finally enters the circulatory system [2]
