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However, we demonstrated that levels and activity of CD38 increase during aging, and that this enzyme is, at least in part, responsible for the age-related NAD decline [6]

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Only ratios of neuronal (NeuN-positive) and non-neuronal (NeuN-negative = glial) cells were estimated in different brain regions of various species 31,32,33,34,35 with about 50% of cells being glia in the mouse cerebral cortex