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Acknowledgements This work was supported by Council of Scientific and Industrial Research (CSIR)- funded project BSC-0104
ML models were run using a custom workflow adapted from the mikropml R package 51,52 ( Only genomes whose metadata for both the health status and country of origin was available were utilised
Off-target effects can also damage normal cells, reducing CAR T cell functionality and viability, thereby compromising therapeutic efficacy and increasing risks
