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Description
Once a drug products range of allowable denaturation has been identified, the next step in this process requires full denaturation of the protein solution as confirmed via physical separations of aggregates or characterization of tertiary or secondary structural changes
[DOI] [PMC free article] [PubMed] [Google Scholar] Glawischnig E

Neilson AP, Ferruzzi MG

Standard doses restore what aging has depleted
