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Knockout of ceruloplasmin and hephaestin was demonstrated to induce iron deposition in mouse astrocytes and oligodendrocytes, respectively [55, 56]
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Consequently, based on the results of several studies on the influence of nutritional ketosis on the course of neurological diseases, KD has been modified
This assumption is further strengthened after observing an increased expression of pro-apoptotic proteins Bim and Puma , the downstream effector of the Bcl-2 family, in the tumor samples having GG- rather than AA-genotype
