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Wound Healing and Regeneration: FOXO4-DRIs senolytic action reduces senescent cell burden in chronic wounds, improving healing outcomes and preventing excessive fibrosis

doi:10.1055/s-0042-1758377

GSH can modulate the activity of various redox-sensitive signaling pathways, including the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, which regulates the expression of antioxidant and detoxification genes, and the mitogen-activated protein kinase (MAPK) pathway, which regulates cell proliferation, differentiation, and apoptosis

Within this review, we focus on analyzing potential associations between the glutathione antioxidant pathway and psychiatric disorders: major depressive disorder, schizophrenia, bipolar disorder, and generalized anxiety disorder