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Description
Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis

Using a randomized allocation protocol, the animals were divided into sham, model, and experimental groups, with the latter further stratified into an MFC group and two SHFKO groups (administered at low and high concentrations)

This profile is further shaped by genetic predisposition, initial microbial exposure at birth, and long-term dietary habits (209)

Although the mechanism of ACO1 and transferrin affecting adipose tissue metabolism is unclear, ACO1 gene expression is significantly related to gene expression of proliferator-activated receptor-gamma coactivator 1-beta (PGC-1), which is critical to the mitochondrial function of adipose tissue [49]
