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NEJM Evid

Daratumumab: a first-in-class CD38 monoclonal antibody for the treatment of multiple myeloma
Ask specific screening questions about pregnancy, lactation, and chronic conditions (pernicious anaemia, cardiac disease, hypertension) that may interact with parenteral B-12 therapy

Weight-Based Dosage Estimates While theres no official dosing chart, many protocols loosely adjust dosage by body weight: Tip: Always begin at the lower end of your range and increase gradually if needed, especially during your first cycle
