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The two compounds engage distinct but complementary research pathways BPC-157 is primarily investigated for angiogenesis, fibroblast migration, and nitric oxide modulation, while TB-500 is studied for G-actin sequestering activity and cytoskeletal reorganization in cell migration

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IL-22 upregulates the expression of CXCL13 in stromal fibroblasts and CXCL12 in epithelial cells (43)

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