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Several potential therapeutic targets related to cholesterol ester metabolism have been identified, including: Acyl-CoA:Cholesterol Acyltransferase (ACAT) : Inhibitors of ACAT, such as avasimibe and pactimibe, reduce cholesterol ester synthesis and intracellular lipid accumulation, offering potential benefits for reducing atherosclerosis progression and improving lipid profiles

[PubMed] [Google Scholar] Ricaurte GA, Mechan AO, Yuan J, Hatzidimitriou G, Xie T, Mayne AH, McCann UD

iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function

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