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The resulting transcriptional upregulation of BDNF supports synaptic differentiation, spine formation, and synaptic efficacy

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Nano-bio interactions: The presence of a multitude of proteins in the blood can bind tenaciously to the surface of nanoparticles, forming a protein crown, which alters their physicochemical characteristics and stability, thereby impeding the specific binding of target molecules to receptors (Ito et al., 1999)

These findings collectively show that astaxanthin, with its high antioxidant characteristics, can be used as an adjuvant treatment in a variety of respiratory disorders, including pneumonia and COVID-19, by lowering oxidative stress and modifying inflammatory responses