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Not only is APAP overdose a clinically relevant model to study hepatocyte cell death and liver injury, but it is also increasingly used to test potential therapeutic intervention strategies

Emerging studies suggest that instead of directly modulating neurotransmitter levels, brain iron overload could indirectly influence neurotransmission through epigenetic mechanisms (Ye et al., 2019

Within 6 months after the first COVID-19 symptom, almost a third of COVID-19 survivors had a neuropsychiatric diagnosis such as insomnia, anxiety and depression [24]
