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Truncation of CGI-58 protein causes malformation of lamellar granules resulting in ichthyosis in Dorfman-Chanarin syndrome
Structurally similar to insulin, IGF-1 binds to specific receptors on cells, activating pathways that promote cell growth, protein synthesis, and repair
Martin T, Dimopoulos M-A, Mikhael J, Yong K, Capra M, Facon T, et al
