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How the Body Defends Itself Your body is built to handle a certain amount of oxidative stress

Altogether, this suggests that basal HO-1 levels are major determinants in the protection against inflammation and possibly atherogenesis, in parallel with our similar findings in the models of liver ischemia reperfusion (Tsuchihashi et al., 2006) and cardiac allograft rejection (see Heme Oxygenase-1 and Vascular Inflammation: Importance of Basal Levels)

Modulation of heme oxygenase-1 expression and activity affects streptozotocin-induced diabetic nephropathy in rats

Karlik M, Valkovic P, Hancinova V, Krizova L, Tothova L, Celec P