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doi: 10.1016/j.neuroscience.2007.06.053, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Chen W., Yan X., Song X., Yang Y., Wang X., Xu G., et al

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In vitro , siFasn and C75 enhanced antioxidant markers Nrf2 and HO-1, reduced ROS accumulation, and suppressed NLRP3 and GSDMD levels

Currently, PAAD is mainly treated by surgery and radiotherapy, but problems such as chemotherapeutic drug resistance have led to a generally poor prognosis for patients, and some studies have confirmed that the development of chemotherapeutic drug resistance is closely related to apoptosis [2], so inducing non-apoptotic cells to die may provide an alternative therapeutic strategy for resisting apoptotic drug resistance