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Adherence to lifestyle-related cancer prevention guidelines and breast cancer incidence and mortality

Future research should prioritize elucidating dynamic iron transport mechanisms across the blood-brain barrier, validating combination therapies targeting synergistic ferroptosis regulators (e.g., Nrf2/GPX4/FSP1), and advancing preclinical findings toward biomarker identification and precision intervention protocols

Under normal circumstances, the redox system within cells is in dynamic equilibrium, with stable production and clearance of ROS