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However, each of the four products can be oxidized to 3-ketosteroids with a concomitant double bond isomerization to give progesterone, 17-hydroxyprogesterone, androstenedione, and testosterone, respectively (Figure 7), and the alternative route to the sex hormones is named the delta4-pathway

So far, it has been described that when reduced by approximately 20%, the levels of ascorbate in cells or plasma inevitably favor the formation of lipid peroxidation products in the whole organism [111,112,113]