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Although the evidence is compelling that cysteine S -conjugate -lyase reactions contribute to the nephrotoxicity of DCVC and other cysteine S -conjugates derived from halogenated alkenes, as noted earlier, the sulfoxides of the cysteine S -conjugate and mercapturates may be even more toxic than the cysteine S -conjugate (Lash et al., 1994, Lash et al., 2003, Werner et al., 1996)

So a patient on a 0.25 mg starter dose draws 25 units per week that is roughly 20 weekly doses per vial

Our ligands were joined with the reported amino acid residues (Gadelmawla et al

Furthermore, recombinant expression systems may not fully replicate the native conditions, potentially leading to altered or incomplete protein functionality