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This is also emphasised by the fact that the direct injection of MDMA into rat brain fails to reproduce the acute or long-term neurotoxic effects evident following peripheral administration (Esteban et al., 2001)
Unlike conventional hormones encoded in nuclear DNA, this peptide is transcribed from the mitochondrial genome and then released into the cytosol and nucleus under stress conditions
[DOI] [PubMed] [Google Scholar] 104.Hanahan D., Weinberg R
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