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Here again, a reasonable initial premise has become untenable in practice

In individuals with T2DM, chronic hyperglycemia is known to downregulate GIPR expression and impair GIP-stimulated insulinotropic activity, thereby limiting the efficacy of GIP monotherapy [21]

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When the BII first opened its laboratories in October 1970, the Institute had 27 scientists, the majority of whom were handpicked by Jerne
