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[PubMed] [Google Scholar] Novinscak T., Brcic L., Staresinic M., Jukic I., Radic B., Pevec D., et al

PURE uniquely enables the study of genetic code architecture, as in vivo changes to the genetic code are largely lethal

In summary, while peptide-based wound dressings offer significant promise owing to their targeted biological activity and potential to enhance healing, numerous scientific, technical, and regulatory challenges still remain to be addressed before their full clinical potential can be realized

As key players in the immune responses of the CNS, both astrocytes and microglia are central to the inception of CNS autoimmunity by regulating autoantigen-presentation, BBB or blood CSF barrier breakdown and aAB leakage, as well as adaptive T- or B-cell activation for aAB production (Ikeshima-Kataoka, 2016