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Description
La reacci qumica s catalitzada per la formaldehid deshidrogenasa, que utilitza GSH com a co-substrat
The accumulation of intracellular ROS caused by low levels of tert-butyl hydroperoxide can induce the activation of p53 and lead to cell death, which can be specifically inhibited by the ferroptosis inhibitor Fer-1 but cannot be inhibited by other kinds of cell death pathway inhibitors, indicating that the form of death is ferroptosis
Lymphoma 62 , 17401748 (2021)
[DOI] [PMC free article] [PubMed] [Google Scholar] Lauterburg BH, Adams JD, Mitchell JR
