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Three derivatives of the D-Nle-X-Ile-(6)amino- hexanoic amide, where X is: Cys, Trp, or Met were examined to determine whether the percent of inhibition of dimerization and the binding affinity for each compound for HGF could be correlated to in vitro cellular activity, namely inhibition of MDCK cell scattering
At the same time, to formulate the SDs, extreme conditions like temperature, pressure, radiation, and organic solvents will be used
Cleveland Clinic Hospital
