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In Achilles tendon transection models in rats, systemic BPC-157 administration via intraperitoneal injection produced significantly improved recovery compared to controls

Gene Expression Analysis Gene expression analysis revealed overlapping patterns between ketamine and BPC-157 effects on Nos1 (neuronal NOS), Nos2 (inducible NOS), Plcg1, Prkcg, and Ptgs2 (COX-2)

Given that both diet composition and adiposity can each substantially impact the gut microflora in obese mice 24 , we conducted a secondary endpoint study using animals given the same series of diets to test the hypothesis that NNMTi treatment combined with LD, but not LD alone, shifts the cecal microbiome profile of obese animals to be similar to age-matched LD controls that were never given a high-fat diet

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