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10.1111/acer.13765 19 EdwardsJ

Hypoxia Inducible Factor 1 (HIF-1), a crucial transcriptional regulator of hypoxic responses, is upregulated under oxidative stress, which subsequently triggers a hypoxic response, enhances the transcription of angiogenic factors, such as vascular endothelial growth factor (VEGF), and mediates autophagy, mitophagy, and aerobic glycolysis [134]

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discussion 192186
