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This can lead to loss of biological activity, significantly limiting its use in nutraceutical applications. Microencapsulation, in contrast, provides a stable, comprehensive solution to astaxanthins chemical instability and sensitivity to oxidation. Gomez added the encapsulation of spirulina further enhances the antioxidant properties of astaxanthin, amplifying the benefits of both compounds

For example, methotrexate, a dihydrofolate reductase (DHFR) inhibitor, is widely used in tumor chemotherapy

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