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There must be an appropriate wash-out period prior to treatment initiation with PDE-5 inhibitors, which will typically be conducted by specialist PH centres

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10.1186/s12937-016-0217-2 4 AnfusoC

Note on humans: These benefits are not established in humans , and the BPC-157 + TB-500 combination is not clinically validated no controlled trials of this blend have been completed [13]