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The mixed pattern suggests individual variation rather than a consistent drug effect

Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells

perphenazine and haloperidol) restrained GBM growth in an orthotopic xenograft model (152, 194)

Moreover, the authors found that the levels of inflammatory markers TNF-, interleukin 6 (IL-6), and matrix metallo-proteinase 9 (MMP-9) were significantly decreased in the CoQ 10 -treated group, while the supplementation did not affect the levels of the anti-inflammatory markers interleukin 4 (IL-4) and tissue growth factor (TGF-), hypothesizing that at the basis of these beneficial effects there are antioxidant and anti-inflammatory activities [89]