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Description
HMG-CoA reductase is recognized as the key enzyme in the regulation of the biosynthesis not only of cholesterol but also of many non-sterol isoprenoids, and this can be regulated by a feedback mechanism after binding of a characteristic element in the second transmembrane helix to Insig, a protein in the endoplasmic reticulum in humans encoded by the insulin induced gene 1

Theyll prescribe whichever antibiotic they believe works best for you and your health history

PMC 272577

doi: 10.1038/nature02099
