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Description
Nanomaterials-based novel immune strategies in clinical translation for cancer therapy

M1 macrophages Classically activated, pro-inflammatory macrophages that express transcription factors such as IRF5, NF-B, AP-1 and STAT1 (as opposed to immunomodulatory, pro-fibrotic M2-spectrum macrophages)

Ratanji, K

Absence of FOXO3a protein results in to downregulation of Keap1 mRNA and FOXM1 targeted genes Apart from the TGF- and Keap1-Nrf2 signaling, mutation in the drug transporter gene could lead to drug resistance
