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In an unadjusted Cox regression model, individuals with the AG genotype and those with the AA genotype were at significantly increased risk of vitamin B 12 deficiency compared with those in the GG genotype reference group (additive model

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NNMT-mediated NAM-metabolome including SAM, SAH, NAD + , and acetyl-CoA and its effects on epigenome need to be characterized in different cancer tissues