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10.1113/jphysiol.2010.203950 J

The researcher is not choosing a format based on conveniencethey are selecting the route that maximizes the probability of the compound reaching its intended site of action at a sufficient concentration

Alhujaily M, Abbas H, Xue M, de la Fuente A, Rabbani N, Thornalley PJ

The break allows a reassessment before deciding whether to run another block
