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Subsequent cell culture studies revealed that GSSG accumulation, as opposed to GSH reduction, sensitized hepatocytes to TNF killing by reducing the TNF-triggered NF-B activity
2020;78(2):21023.e8
GSH is on the front lines of your defense against free radicals, which are the DNA-damaging compounds found in pollutants, cigarette smoke, and sun overexposure
Alternatively, serine can be converted to 3-hydroxypyruvate via transamination of pyruvate catalyzed by alanineglyoxylate and serinepyruvate aminotransferase 2 (encoded by the AGXT2 gene)
