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GPS mitigates this by suppressing the release of pro-inflammatory cytokines like TNF- and IL-6 at the wound site (Wang et al., 2020

J Radiat Res Appl Sci 18(4):102010 Ozturk S (2015) Telomerase activity and telomere length in male germ cells

Given that hyperglycemia in animal models and humans is associated with poor adaptive response to aerobic training 1,2,3,6 , we attribute the reversal of exercise resistance in STZ-KETO to glucose normalization

All chromatography buffers were prepared in Milli-Q Ultrapure water (MilliporeSigma, Burlington, MA) with 1015 mM Tris-HCl (Thermo Fisher Scientific) and 0.005% Polysorbate 80 (PS80) (Croda, Snaith, United Kingdom), and the indicated sodium chloride (NaCl) (Teknova, Hollister, CA) concentration and pH were adjusted with either 50% sodium hydroxide (NaOH) (Thermo Fisher Scientific) or 37% hydrochloric acid (Thermo Fisher Scientific)