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The FDA label includes a boxed warning regarding thyroid C-cell tumors observed in rodent studies, contraindicating use in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

Under abnormal metabolic conditions, such as hypoxia, ROS are primarily produced by complexes I and III

[DOI] [PubMed] [Google Scholar] 27.Li MF, Cheung BM

J Toxicol Clin Toxicol 40:320 Schidt FV, Rochling FA, Casey DL, Lee WM (1997) Acetaminophen toxicity in an urban county hospital
