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Therefore, we created three C-terminal active site mutants of hTrxR1 (hTrxR1 C497S,U498C , hTrxR1 U498S , and hTrxR1 C497_trunc ) and tested them against three mutants of hTrx1 (hTrx1 C73S , hTrx1 C32S,C73S , and hTrx1 C35S,C73S

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