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We included studies published in English without publication year restrictions and screened the reference lists of included articles to identify additional relevant studies

Comparison: Melanotan II vs conventional tanning Why regulators have warned about it The FDA has not approved Melanotan II, and agencies in several countries have warned against buying unlicensed Melanotan products online

PPAR is able to upregulate the expression of almost all genes involved in the carnitine shuttle mechanism (e.g., CPT1, CPT2, CACT and CrAT) [193, 194]