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In a randomized trial, objective vitiligo repigmentation obtained with topical catalase/dismutase superoxide (C/DSO) treatment is similar to topical 0.05% betamethasone [102], highlighting the need for better antioxidant medications
high concentrations of 4HNE have been associated with apoptosis, altered gene expression, neurodegenerative and cardiovascular diseases, cancer and metabolic syndrome [33,34,35]
