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Additionally, the amenability of PLGA nanosystems to functionalization by ligands (lactoferrin) or polymers (PEG) could facilitate targeted delivery, ensuring efficient delivery of their cargos to target tissues and thus minimizing off-target effects 31

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Why this matters: By 3 months, an infants digestive and metabolic systems are more developed Early postpartum milk supply has stabilized Maternal recovery is more established Risk assessment becomes clearer for healthcare providers This does not mean automatic approval, it means discussion becomes possible , not assumed