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While some dogs may show no immediate signs, the condition can silently progress, leading to severe complications such as congestive heart failure or sudden cardiac events

Even habits like sun exposure, hydration, or how often you move your facial muscles can subtly change their appearance

An inability of the GT II assay to identify the genotype 1 subtype may be due to (i) the presence of genetic variability in the NS5B region in which the probes specific for subtype 1a or 1b detection anneal (majority in the present study), (ii) the presence of rare HCV-1 subtypes (four cases observed), or (iii) the presence of certain genotype 6 subtypes in which the 5NC region targeted by the genotype 1-specific probe is identical to some 1b subtypes 11,13,33 (none observed in our study)