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However, a small number of GHR antagonists are in clinical trials or preclinical development, and we anticipate that these will eventually expand the options available for clinical and research applications

PMID: 34571860
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In addition, disfunction of the photosynthesis process leads to enhanced accumulation of ROS and to formation of oxidative dependent lesions ( 2 -G, increased levels of this modification was observed in total RNA and mRNA of potato plants in response to the inoculation with the pathogen Phytophthora infestans