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[DOI] [PubMed] [Google Scholar] 86.Marklund SL

GPx1 knockout mice were shown to have improved sensitivity to insulin compared with GPx1 overexpressing mice

Although there is a broad clinical spectrum of glutathione synthetase deficiency, manifestations usually include hemolytic anemia, often include metabolic acidosis, and sometimes include progressive neurologic symptoms as well as other systemic signs (eg, respiratory distress, sepsis, hyperbilirubinemia) (62
