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In the first half reaction, NADPH reduces FAD present in glutathione reductase to produce a transient FADH- anion, which breaks a disulfide bond of Cys58 - Cys63, forming a short-lived covalent bond between the flavin and Cys63
Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice

Cell Rep (2017) 20(7):170516
