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However, in a much larger randomized controlled trial of simvastatin and an antioxidant combination of 600 mg of all - rac --tocopherol (297 mg of RRR --tocopherol), 250 mg of vitamin C, and 20 mg of -carotene daily) in more than 20,000 men and women with CHD or diabetes mellitus, the antioxidant combination did not adversely affect the cardioprotective effects of simvastatin therapy over a five-year period (131)

Effects of cholecystokinin and bombesin on the expression of preprosomatostatinencoding genes in goldfish forebrain

however, it results in increased levels of hydrogen peroxide and defects in certain cellular pathways

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