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Activated PI3K autophosphorylates its inositol ring and the p85 regulatory subunit and p110 catalytic subunits, which is followed by phosphorylation and activation of protein kinase B/Akt (PKB/Akt)

10.1016/j.watres.2015.02.032

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Administration of BPC-157 at a dose of 10 g/kg or 10 g/kg after lidocaine administration reduced the bradycardia effect within minutes
