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A direct correlation between increased metabolism of docetaxel, flutamide, paclitaxel, and mitoxantrone because of increased expression of CYP1B1 (cytochrome P450 1B1) and the onset of MDR in various cancer cells has been drawn out by researchers, as is the case with overexpression of the CYP2A6 (cytochrome P450 2A6) enzyme in breast tumour cells, whereby it is reported to enhance the metabolism of drugs like aflatoxin, cyclophosphamide, ifosfamide, and fluorouracil [54]

While these findings are still preliminary, they point to MOTS-c as a potential factor in maintaining bone health

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In each well, 180 L of diluted nanosensor protein and 20 L from each solution were taken