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Studies have indicated that the increase of the autophagy level in vivo can lead to the degradation of ferritin and the increase of iron level, thus leading to oxidative damage of cells through the Fenton reaction [66, 67]

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Mayerhofer, A

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10.1016/j.cell.2018.12.013 Cell 132 ReeveA.MeagherM.LaxN.SimcoxE.HepplewhiteP.JarosE.et al (2013)

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