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It is an investigational compound, not an FDA-approved medication

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Improving Intestinal Barrier Integrity to Limit Inflammatory Disease Development Given the negative impact of environmental and genetic factors, it is important to be aware of the strategies that exist which aim to improve gut barrier integrity and overall functioning

3 Role of immune cells in the pathogenesis of DKD 3.1 Macrophages Macrophages, which originate from circulating monocytes, are central innate immune cells that polarize into pro-inflammatory M1 or anti-inflammatory/pro-fibrotic M2 phenotypes in response to microenvironmental cues (50)
